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. 2017 Oct 11;37(5):BSR20170768. doi: 10.1042/BSR20170768

Table 2. Enriched KEGG pathways involving target genes of 30 low-abundance miRNAs (P<0.05).

Pathway ID Definition Hits Total Percent (%) Fisher-P value
cfa05206 MiRNAs in cancer 31 139 22.30% 2.70E-05
cfa05200 Pathways in cancer 62 393 15.78% 4.29E-04
cfa04010 MAPK signaling pathway 43 252 17.06% 6.55E-04
cfa04060 Cytokine–cytokine receptor interaction 38 216 17.59% 7.35E-04
cfa04151 PI3K-Akt signaling pathway 53 334 15.87% 9.73E-04
cfa03060 Protein export 8 23 34.78% 1.55E-03
cfa04933 AGE-RAGE signaling pathway in diabetic complications 21 102 20.59% 1.57E-03
cfa04510 Focal adhesion 35 204 17.16% 1.84E-03
cfa04810 Regulation of actin cytoskeleton 36 212 16.98% 1.92E-03
cfa04974 Protein digestion and absorption 18 84 21.43% 2.08E-03
cfa04062 Chemokine signaling pathway 30 172 17.44% 2.94E-03
cfa04722 Neurotrophin signaling pathway 22 120 18.33% 5.56E-03
cfa04320 Dorsoventral axis formation 8 28 28.57% 6.14E-03
cfa05205 Proteoglycans in cancer 32 197 16.24% 6.65E-03
cfa04666 Fc γ R-mediated phagocytosis 17 88 19.32% 8.25E-03
cfa04068 FoxO signaling pathway 23 132 17.42% 8.72E-03
cfa04668 TNF signaling pathway 19 105 18.10% 1.10E-02
cfa04670 Leukocyte transendothelial migration 21 120 17.50% 1.13E-02
cfa04360 Axon guidance 22 128 17.19% 1.19E-02
cfa04550 Signaling pathways regulating pluripotency of stem cells 23 138 16.67% 1.47E-02
cfa05212 Pancreatic cancer 13 65 20.00% 1.48E-02
cfa00310 Lysine degradation 11 52 21.15% 1.60E-02
cfa04115 p53 signaling pathway 13 66 19.70% 1.67E-02
cfa04350 TGF-β signaling pathway 15 82 18.29% 2.04E-02
cfa04512 ECM–receptor interaction 15 82 18.29% 2.04E-02
cfa05222 Small cell lung cancer 15 84 17.86% 2.50E-02
cfa04919 Thyroid hormone signaling pathway 19 115 16.52% 2.72E-02
cfa02010 ABC transporters 9 43 20.93% 2.99E-02
cfa05166 HTLV-I infection 35 246 14.23% 3.26E-02
cfa04064 NF-κB signaling pathway 15 87 17.24% 3.32E-02
cfa05202 Transcriptional misregulation in cancer 24 158 15.19% 3.59E-02
cfa05220 Chronic myeloid leukemia 13 73 17.81% 3.61E-02
cfa05146 Amoebiasis 16 96 16.67% 3.77E-02
cfa04917 Prolactin signaling pathway 13 74 17.57% 3.98E-02
cfa04144 Endocytosis 35 252 13.89% 4.42E-02
cfa04620 Toll-like receptor signaling pathway 16 98 16.33% 4.44E-02
cfa04014 Ras signaling pathway 31 220 14.09% 4.74E-02
cfa00603 Glycosphingolipid biosynthesis – globo series 4 14 28.57% 4.96E-02