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. 2018 May 22;16:138. doi: 10.1186/s12967-018-1516-5

Fig. 1.

Fig. 1

Growth curves of lung cancer PDXs in SCID mice. a The generation harboring the patient-derived tumor tissue was termed P0, with subsequent generations numbered consecutively (P1, P2, P3 and so on). The growth of PDX xenografts reaches a steady state level in third and more passages. Growth curves of three passage xenografts (1st, 2nd and 3rd passage) plotted as tumor volume in PDX xnografts LG33. b The tumor volume of 1st, 2nd and 3rd passage was measured in lung adenocarcinoma LG50