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. 2018 May 22;16:138. doi: 10.1186/s12967-018-1516-5

Table 2.

Summary statistics for identified SNPs for LG50 tumor tissue, primary cell line and PDX xenografts

Samples Total SNPs Fraction of SNPs in dbSNP (%) Fraction of SNPs in 1000 genomes (%) Novel Homozygous Heterozygous Intron 5′ UTRs 3′ UTRs Upstream Down stream Intergenic Ti/Tv
Patient tumor tissue 102,402 98.23 95.81 1473 1473 54,009 69,062 1567 3298 2077 1538 2330 2.34
Primary cell line 94,847 98.23 95.81 1473 44,541 50,306 62,661 1426 2974 1793 1377 2188 2.35
PDX tumor tissue 95,908 94.59 92.17 1473 44,875 51,033 61,376 1468 3130 1778 1359 2170 2.33