TABLE 1.

PROTEIN TARGETS FOR POLYAMIDE INHIBITORS

Protein	DNA-Binding Motif	Gene Target
TFIIIA	zinc finger	5S ribosomal RNA
TBP/TFIID	minor groove/saddle	mRNA-coding genes
LEF-1	HMG box	HIV-1
Ets-1	winged-helix–turn–helix	HIV-1
IE-86	minor groove	CMV MIEP
Estrogen receptor	C4 zinc finger	estrogen-responsive genes
Deadpan	basic helix–loop–helix	Drosophila neural genes
GCN4	bZip	yeast mRNA-coding genes
Tax	minor groove	HTLV-I