Figure 1.
(A) Delivery strategy of LHRH-PEG-PHis-DOX/DOX-TAT micelles. (B) Images of the tumors on day 14 after the inoculation of A2780/DOXR tumor cells in the mice and in vivo antitumor efficacy.
Notes: Reprinted from Yang T, Li F, Zhang H, et al. Multifunctional pH-sensitive micelles for tumor-specific uptake and cellular delivery. Polym Chem. 2015;6(8):1373–1382.34 With permission from the Royal Society of Chemistry. Copyright 2014 Royal Society of Chemistry.
Abbreviations: LHRH, luteinizing hormone-releasing hormone; PEG, poly(ethylene glycol); PHis, poly(histidine); DOX, doxorubicin; TAT, trans-activating transcriptional activator.
