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. 2018 May 18;11:2945–2954. doi: 10.2147/OTT.S165436

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© 2018 Wu et al. This work is published and licensed by Dove Medical Press Limited

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Triclosan decreased the antitumor effect of sorafenib on MHCC97-H cell intrahepatic model.

Notes: MHCC97-H cells were injected into nude mice’s liver lope to form intrahepatic tumors. Mice were divided into four groups: 1) solvent control, 2) sorafenib, 3) triclosan, and 4) sorafenib + triclosan. The tumor nodules formed by MHCC97-H cells in mice’s liver were examined by PET/CT scanning. Results are shown as (A) PET/CT results from animals or radioactivation of liver to blood and (B) tumor organs or PET/CT results from liver organs. *P<0.05 solvent control group versus triclosan group; solvent control group versus sorafenib group.

Abbreviation: PET/CT, positron emission tomography/computed tomography.