. 2018 Jan 10;91(1083):20170220. doi: 10.1259/bjr.20170220

Table 2.

Frequency of the hypodense sign in proven, probable and possible IMD (127 patients) by EORTC diagnostic criteria

EORTC diagnostic category	Frequency in all patients	Hypodense sign without contrast (HRCT)	Hypodense sign with contrast CT arterial phase (CTPA)	Hypodense sign with contrast CT venous phase
n = 127 (%)	n = 20 (15.7%)	n = 56 (44.1%)	n = 19 (51.3%)^a
Proven IMD	15 (11.8)	6 (40.0)	13 (86.7)	5 (100)
Probable IMD	41 (32.3)	12 (29.3)	32 (78.0)	10 (71.4)
Possible IMD	71 (55.9)	2 (2.8)	11 (15.5)	4 (22.2)
Highly possible IMD^b	30 (23.6)	2 (6.7)	10 (33.3)	4 (40.0)
No IMD^c	41 (32.3)	0 (0)	1 (2.4)	0 (0)

CTPA, CT pulmonary angiography; EORTC, European Organization for Research and Treatment of Cancer; HRCT, high-resolution CT; IMD, invasive mould disease.

^aValues related to 37/127 (29.1%) patients who carried out CT venous phase (5 proven IMD; 14 probable IMD; 18 possible IMD; 10 highly possible IMD).

^bNo evidence of an alternative diagnosis and patient responded to antifungal therapy.

^cIncluding 27 bacterial pneumonia.