Table 4.

Densitometric analysis of lesions in IMD vs non-IMD cases (98/127 patients)

Patients	Area of analysis	Positive HyS			Negative HyS
HRCT(n = 18)	CTPA(n = 45)	VP(n = 15)	HRCT(n = 47)	CTPA(n = 20)	VP(n = 5)
IMD 65/98	Peripheral	36.55	46.84	64.13	27.72	44.35	53.88
Centre	20.22	21.78	25.20	20.68	41.44	51.60
Difference	16.33	25.06	38.93	7.04	2.91	2.28
		HRCT(n = 0)	CTPA(n = 1)	VP(n = 0)	HRCT(n = 33)	CTPA(n = 32)	VP(n = 13)
No-IMD 33/98	Peripheral	–	37.03	–	24.85	54.82	60.92
Centre	–	13.25	–	23.67	52.73	58.77
Difference	–	23.78	–	1.18	2.09	2.15

CTPA, CT pulmonary angiography; HRCT,high-resolution CT; HyS,hypodense sign; IMD, invasive mould disease; VP, venous phase.

The average HU values of the pulmonary lesions in peripheral zone, central zone, and the difference between peripheral and central zone, respectively on unenhanced HRCT, arterial phase (CTPA) and VP, are compared with evaluation of HyS, in both the two groups of patients, with IMD and without IMD.