Table 3.

Key DVH metrics of patient cohort for rectum and bladder OARs, median (min–max)

OAR	Metric	Constraint	Pre-spacer plans	Post-spacer plans
Rectum	DMean (Gy)		15.0 (13.8–16.9)	13.4a (9.9–14.9)
D2cc (Gy)		36.3 (34.1–37.8)	31.1a (21.5–33.6)
V18.1 Gy (%)	<50%	33.0 (30.0–44.2)	28.0a (11.9–33.4)
V29 Gy (%)	<20%	14.1 (9.4–15.7)	5.9a (0.0–6.6)
V36 Gy (cc)	<1 cc	2.6 (1.0–4.1)	0.3a (0.0–1.0)
V38 Gy (cc)		0.5 (0.2–1.7)	0.1 (0.0–0.3)
Bladder	DMean (Gy)		8.5 (5.8–11.1)	9.2 (5.8–15.3)
D2 cc (Gy)		39.9 (38.7–41.1)	39.6 (38.1–41.6)
V18.1 Gy (%)	<40%	20.6 (11.0–25.4)	21.7 (11.9–38.5)
V37 Gy (cc)	<10cc	6.9 (4.4–13.9)	7.0 (3.4–12.5)

DVH, dose volume histogram; OAR, organ at risk.

^ap ≤ 0.05 considered statistical significant.