Table 2.
Tumour size (GTV) and motion (ITV), and associated motion of GTV centroid as measured during simulation ; data from 4DCT and free-breathin g (172 s) MRI (bottom row)
Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 | ||||||
Simulation | Contour size (mm) | Motion (mm) | Contour size (mm) | Motion (mm) | Contour size (mm) | Motion (mm) | Contour size (mm) | Motion (mm) | Contour size (mm) | Motion (mm) |
CT GTVa | 28.7 | – | 43.2 | – | 27 | – | 14.6 | – | 14.8 | – |
4DCT ITVa | 41.7 | 13 | 49.8 | 6.6 | 31.6 | 4.6 | 21.1 | 6.5 | 21.2 | 6.4 |
FB MRI ITVa | 38.9 | 10.2 | 59.3 | 16.1 | 35.6 | 8.6 | 21.9 | 7.3 | 23.7 | 8.9 |
Location | Right lower lung | Right lower lung | Right upper lung | Right medial lung | Right medial lung | |||||
aMeasured along dimension of maximum motion, through the central slice | ||||||||||
Cine mode | Mean motion (mm) | σ (mm) | Mean motion (mm) | σ (mm) | Mean motion (mm) | σ (mm) | Mean motion (mm) | σ (mm) | Mean motion (mm) | σ (mm) |
Fraction 1 | 11.1 | 2.0 | 9.4 | 2.0 | 8.4 | 1.7 | 1.9 | 1.2 | ||
Fraction 2 | 13.7 | 1.3 | 11.0 | 2.2 | 3.0 | 1.2 | 3.5 | 0.9 | ||
Fraction 3 | 18.0 | 3.0 | 6.0 | 0.8 | 4.8 | 1.5 | 2.0 | 0.4 | ||
Fraction 4 | 15.2 | 3.3 | – | – | 5.1 | 1.1 | – | – | – | – |
Cine mode measured motion (mean and standard deviation) of GTV centroid.