Table 3. Measures of fat distribution and lean body mass association with impaired fasting glucose, hypertriglyceridemia, hypertension and insulin resistance in men and women.
| Z-Waist OR (95% CI) | Z-Android fat OR (95% CI) | Z-Visceral fat OR (95% CI) | Z- abdominal SAT OR (95% CI) | Z-arm fat OR (95% CI) | Z-Hip OR (95% CI) | Z-Gynoid fat OR (95% CI) | Z-Leg fat OR (95% CI) | Z-lean body mass OR (95% CI) | |
|---|---|---|---|---|---|---|---|---|---|
| MODEL 1 | |||||||||
| Men (n=2119) | |||||||||
| Impaired fasting glucose (n=626) | 1.62 (1.46, 1.80) | 1.71 (1.53, 1.90) | 1.79 (1.60, 2.01) | 1.39 (1.26, 1.55) | 1.41 (1.28, 1.56) | 1.39 (1.26, 1.54) | 1.51 (1.36, 1.68) | 1.37 (1.24, 1.52) | 1.18 (1.06, 1.31) |
| Hypertriglyceridemia (n=661) | 2.48 (2.20, 2.79) | 2.78 (2.45, 3.15) | 3.27 (2.85, 3.76) | 1.69 (1.51, 1.87) | 2.10 (1.87, 2.34) | 1.81 (1.63, 2.02) | 1.95 (1.74, 2.17) | 1.66 (1.49, 1.84) | 1.32 (1.18, 1.46) |
| Hypertension (n=377) | 1.88 (1.66, 2.14) | 1.95 (1.70, 2.23) | 2.17 (1.89, 2.50) | 1.41 (1.24, 1.59) | 1.56 (1.37, 1.76) | 1.55 (1.37, 1.75) | 1.51 (1.33, 1.72) | 1.36 (1.20, 1.53) | 1.16 (1.02, 1.31) |
| Insulin resistance (n=647) | 2.74 (2.41, 3.10) | 3.68 (3.21, 4.23) | 3.16 (2.74, 3.62) | 2.01 (1.80, 2.26) | 2.11 (1.88, 2.36) | 1.92 (1.72, 2.14) | 2.21 (1.97, 2.49) | 1.86 (1.67, 2.09) | 1.39 (1.24, 1.54) |
| Women (n=2831) | |||||||||
| Impaired fasting glucose (n=285) | 2.21 (1.90, 2.53) | 2.33 (2.01, 2.69) | 2.58 (2.21, 3.01) | 1.98 (1.72, 2.28) | 1.94 (1.69, 2.23) | 1.89 (1.65, 2.17) | 1.82 (1.58, 2.08) | 1.59 (1.39, 1.82) | 1.32 (1.14, 1.53) |
| Hypertriglyceridemia (n=281) | 2.68 (2.31, 3.11) | 2.91 (2.49, 3.39) | 3.44 (2.92, 4.06) | 2.32 (2.01, 2.68) | 2.34 (2.02, 2.71) | 1.91 (1.67, 2.19) | 1.83 (1.59, 2.09) | 1.63 (1.43, 1.86) | 1.33 (1.15, 1.54) |
| Hypertension (n=194) | 1.95 (1.66, 2.29) | 1.96 (1.67, 2.32) | 2.18 (1.84, 2.58) | 1.71 (1.45, 2.01) | 1.73 (1.47, 2.02) | 1.64 (1.40, 1.92) | 1.48 (1.27, 1.73) | 1.33 (1.13, 1.54) | 1.03 (0.86, 1.22) |
| Insulin resistance (n=505) | 3.43 (3.00, 3.92) | 3.03 (2.64, 3.46) | 4.03 (3.48, 4.66) | 2.99 (2.63, 3.39) | 2.95 (2.60, 3.35) | 2.56 (2.27, 2.89) | 2.45 (2.18, 2.76) | 2.06 (1.83, 2.30) | 1.37 (1.22, 1.54) |
| MODEL 2 | |||||||||
| Men (n=2119) | |||||||||
| Impaired fasting glucose (n=626) | 1.07 (0.86, 1.34) | 1.93 (1.30, 2.88) | 1.69 (1.36, 2.11) | 0.73 (0.61, 0.87) | 0.56 (0.43, 0.72) | 0.82 (0.69, 1.02) | 0.79 (0.61, 1.03) | 0.61 (0.49, 0.76) | 1.07 (0.95, 1.20) |
| Hypertriglyceridemia (n=661) | 1.83 (1.45, 2.32) | 5.01 (3.25, 7.69) | 3.64 (2.82, 4.70) | 0.56 (0.47, 0.67) | 0.73 (0.57, 0.96) | 0.89 (0.75, 1.06) | 0.44 (0.34, 0.58) | 0.32 (0.25, 0.41) | 1.10 (0.98, 1.25) |
| Hypertension (n=377) | 1.16 (0.88, 1.53) | 2.65 (1.63, 4.31) | 2.49 (1.88, 3.31) | 0.55 (0.45, 0.67) | 0.58 (0.43, 0.79) | 0.91 (0.75, 1.11) | 0.44 (0.32, 0.61) | 0.38 (0.29, 0.50) | 0.97 (0.84, 1.13) |
| Insulin resistance (n=647) | 1.54 (1.21, 1.98) | 3.89 (2.51, 6.02) | 2.36 (1.83, 3.02) | 0.70 (0.57, 0.84) | 0.48 (0.36, 0.63) | 0.80 (0.67, 0.96) | 0.57 (0.42, 0.75) | 0.39 (0.31, 0.50) | 1.14 (0.92, 1.29) |
| Women (n=2831) | |||||||||
| Impaired fasting glucose (n=285) | 1.40 (1.06, 1.85) | 2.69 (1.67, 4.34) | 2.39 (1.83, 3.13) | 0.59 (0.41, 0.87) | 0.76 (0.55, 1.06) | 0.81 (0.62, 1.05) | 0.57 (0.42, 0.78) | 0.50 (0.38, 0.64) | 1.07 (0.91, 1.28) |
| Hypertriglyceridemia (n=281) | 1.63 (1.23, 2.18) | 4.15 (2.52, 6.82) | 3.57 (2.67, 4.78) | 0.63 (0.43, 0.93) | 0.88 (0.63, 1.23) | 0.48 (0.38, 0.63) | 0.25 (0.18, 0.35) | 0.30 (0.23, 0.40) | 1.09 (0.91, 1.31) |
| Hypertension (n=194) | 1.41 (1.02, 1.94) | 2.38 (1.37, 4.16) | 2.22 (1.63, 3.02) | 0.61 (0.38, 0.93) | 0.87 (0.59, 1.29) | 0.84 (0.62, 1.15) | 0.41 (0.28, 0.58) | 0.41 (0.31, 0.55) | 0.88 (0.72, 1.08) |
| Insulin resistance (n=505) | 1.75 (1.38, 2.23) | 3.43 (2.27, 5.18) | 2.84 (2.24, 3.60) | 0.82 (0.59, 1.13) | 0.95 (0.71, 1.26) | 0.69 (0.56, 0.86) | 0.43 (0.33, 0.56) | 0.36 (0.29, 0.45) | 1.13 (0.98, 1.31) |
Estimates presented as odds ratios (OR) and 95% confidence interval (CI) and represent risk of outcome with 1 s.d. increase in adiposity measurement. †Model 1: adjusted for age, smoking, physical activity, alcohol intake. ‡Model 2: adjusted for age, smoking, physical activity, alcohol intake and BMI for waist and hip circumferences/FMI for DXA-derived depots.