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. Author manuscript; available in PMC: 2018 May 23.
Published in final edited form as: J Am Chem Soc. 2018 Apr 17;140(16):5612–5624. doi: 10.1021/jacs.8b02271

Figure 6.

Figure 6

Uptake assay for rhodium metalloinsertors and controls. [Rh(phen)(chrysi)(PPO)]2+ (phen), [Rh(bpy)2(chrysi)]3+ (Rh-BC), [Ru(DIP)2(chrysi)]2+ (Ru- DIP), and RbCl accumulation in HCT116O cells was measured by ICP-MS analysis after treatment with or without metabolic inhibitors (oligomycin and 2-deoxy-D-glucose). Rhodium, ruthenium, and rubidium contents were normalized to protein content determined by BCA assay. Each experiment was performed in triplicate and averaged, with error shown as the standard deviation. Each experiment was repeated three times with similar outcomes (not shown). RbCl* indicates that Rb concentrations for RbCl have been lowered by a factor of 500 in this graphic.