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. Author manuscript; available in PMC: 2018 Jun 13.
Published in final edited form as: Nature. 2017 Dec 13;552(7685):404–409. doi: 10.1038/nature25144

Extended Data Figure 6. Effector-stage de novo DNA methylation is enriched at genes that regulate effector and memory T cell differentiation.

Extended Data Figure 6

A) Normalized graph of Dnmt3a-mediated de novo methylation at CpG sites in the Lef1 and IL6ST loci from WGBS data sets. B) Summary graph of maintenance methylated regions in WT and Dnmt3a cKO effector WGBS datasets. C) Connectivity plot showing IPA predicted interactions of ID2 and ID3 with Dnmt3a-targeted loci.