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. Author manuscript; available in PMC: 2018 Jun 13.
Published in final edited form as: Nature. 2017 Dec 13;552(7685):404–409. doi: 10.1038/nature25144

Extended Data Figure 9. CD62L low MP effector CD8 T cells develop into Tcm CD8 T cells.

Extended Data Figure 9

A) Representative FACS analysis of CD62L expression on Thy1.1+ CFSE+ MP and TE CD8 T cells 1 day post transfer into naïve recipient mice. The limit of our detection was ~10-20 CD62L+ cells in each of the lymphoid and nonlymphoid tissues at 1 day post-transfer. B) Summary graph of number of transferred TE and MP CD8 T cells in the spleen, blood, lymph node, IEL, lung, and liver of the recipient mice 1 day post-transfer. C) Summary graph of percent undivided (undiluted CFSE) CD62L positive virus-specific memory CD8 T cells arising from adoptively transferred MP vs. TE cells. Data are from 3 independent experiments. D) Representative post-sort purity FACS analysis of undivided CD62Lhi and CD62Llo MP P14 cells 28 days after adoptive transfer.