Figure 1.
Expression of Nm23-H1 in different BJAB cell lines and the Oligo GE array analysis. Western blot showed about 20-fold overexpression of Nm23-H1 protein in clone 10 cells (used for experiments) compared to clone 6 cells (highly metastatic). The same blot was stripped and probed with actin to demonstrate equal loading. As shown in same Figure, RT-PCR analysis showed 2.2-fold overexpression of nm23 transcript in clone 10 cell line compared to clone 6. The right panel showing the trend of the individual array of the specific pathway (Apoptosis, cell cycle and p53 pathway).