Table 2.
Association of number (by type) of medications and risk of lifetime and past-year non-fatal overdosea
| Medication type | Lifetime Overdose OR (95%CI) |
p-value | Past-year Overdose OR (95%CI) |
p-value |
|---|---|---|---|---|
| Each additional overall medication | 1.05 (1.00, 1.10) | 0.06 | 1.06 (0.99, 1.14) | 0.12 |
| Each additional non-antiretroviral medication | 1.05 (1.00, 1.10) | 0.08 | 1.07 (1.00, 1.15) | 0.048 |
| Each additional sedating medication b | 1.26 (1.08, 1.46) | 0.003 | 1.18 (1.00, 1.39) | 0.049 |
| Each additional non-sedating medication b | 0.99 (0.94, 1.06) | 0.84 | 1.02 (0.92, 1.14) | 0.67 |
a
Results of separate unadjusted logistic regression models examining the association of the number of medications in each category and each type of overdose. Lifetime non-fatal overdose analyses included 249 observations. (One participant declined to respond to the question about overdose). Past-year overdose analyses were generalized estimating equations logistic regression models using 482 observations: 249 at baseline and 233 at 12 months. Results of adjusted models were not substantially different (Appendix).
b
Results of one model “number of sedating medications” and ”number of non-sedating medications”