Table 1.
Serum concentrations (ng/mL) of cortisol and corticosterone in rabbits (n = 10 per group)
| Cortisol |
Corticosterone |
|||||
| Group 1 | Group 2 | Group 3 | Group 1 | Group 2 | Group 3 | |
| 0 min | 2.60 ± 0.39 | 2.88 ± 0.45 | 2.67 ± 0.42 | 7.25 ± 1.01 | 7.63 ± 0.89 | 7.27 ± 1.07 |
| 5 min | 2.92 ± 0.38 | 5.54 ± 0.71 | 19.67 ± 3.45a | 7.49 ± 0.86 | 3.89 ± 0.43 | 21.62 ± 3.15a |
| 10 min | 2.83 ± 0.39 | 4.68 ± 0.69 | 19.31 ± 2.78a | 7.03 ± 0.79 | 5.82 ± 0.61 | 17.82 ± 2.21a |
| 30 min | 2.69 ± 0.37 | 3.94 ± 0.77 | 18.91 ± 2.60a | 6.71 ± 0.91 | 8.77 ± 0.99 | 23.57 ± 3.12a |
| 60 min | 2.46 ± 0.30 | 3.44 ± 0.51 | 20.27 ± 2.35a | 6.75 ± 0.97 | 7.95 ± 0.95 | 25.57 ± 3.45a |
| 24 h | 2.67 ± 0.45 | 3.11 ± 0.44 | 3.03 ± 0.41 | 7.23 ± 0.67 | 8.99 ± 0.82 | 7.42 ± 1.33 |
Group 1 received normal saline intravenously; group 2 received propofol (3 mg/kg IV) and dexmedetomidine (0.35 mg/kg IM); and group 3 received propofol (3 mg/kg IV) and ketamine (1 mg/kg IV). All values are expressed as mean ± SD.
Value is significantly (P < 0.001) different from the baseline value (0 min) and compared with groups 1 and 2 at the same time point.