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. 2018 May 11;9(36):24457–24469. doi: 10.18632/oncotarget.25326

Figure 5. Analysis of the expression and DNA methylation of miR-200b in clinical BCa tumors using TCGA data sets.

Figure 5

(A) Locations of Infinium BeadChip probes in the CpG island of miR-200b. Genomic locations are based on Human GRCh38/hg38. (B) Correlation between levels of miR-200b expression and DNA methylation of the indicated probe in primary BCa (n = 345). The Pearson's correlation coefficient (R) is also shown. (C) Kaplan–Meier curve showing the effect of miR-200b expression on overall survival of BCa patients (n = 353). (D) Kaplan–Meier curve showing the effect of DNA methylation of the indicated probe on overall survival of BCa patients (n = 347). (E) Correlation between levels of miR-200b expression and expression of HAS2 (left) or ZEB1 (right) in primary BCa (n = 345). (F) Kaplan–Meier curves showing the effects of HAS2 (left) and ZEB1 (right) expression on recurrence-free survival among patients with stage 2 or higher BCa (n = 275).