Table 1.
Summary of growth in MPS
| MPS | Ethnic Population | Mean Birth Length (cm) | Mean Birth Weight (kg) | Mean Birth BMI (kg/m2) | Mean Final* Height (cm) | Mean Final* Weight (kg) | Mean Final* BMI (kg/m2) | Relationship with Cognitive Impairment |
|---|---|---|---|---|---|---|---|---|
| I | Polish3 (n = 16, all male) | 55.3 ± 3.7 | 3.43 ± 0.7 | 11.2 | - | - | - | Yes |
| II | Japanese10 (n= 111, all male) | 50.31 ± 1.42 | 3.35 ± 0.39 | 13.2 ± 3.29 | 125.63 ± 9.09 | 37.18 ± 8.72 | 29.41 ± 6.15 | No |
| Korean11 (n = 32, all male) | - | - | - | 127.7 (median, n = 7) | - | - | No | |
| Mixed7 (n = 676, all male) | - | - | - | - | - | - | No | |
| III | Dutch13 (n = 118) | 50.6 ± 1.7 | 3.5 ± 0.582 | 13.7 | Males: 169.7 ± 9.3 | Males: 60.1 ± 9.9 | Males: 20.4 ± 2.2 | Yes |
| Females: 165.4 ± 9.9 | Females: 61.1 ± 11.6 | Females: 20.2 ± 2.7 | ||||||
| IVA | Mixed6 (n = 388; 195 males, 193 females) | Males: 52.4 ± 3.93 | Males: 3.56 | Males: 13.0 | Males: 119.3 ± 22.6 | Males: 36.5 ± 13.2 | Males: 24.7 ± 6.1 | N/A |
| Females: 52.1 ± 2.90 | Females: 3.50 | Females: 12.9 | Females: 113.5 ± 23.1 | Females: 35.2 ± 13 | Females: 25.6 ± 5.4 | |||
| Mixed14 (n = 354; 188 males, 166 females) | Males: 52.5 ± 4.0 | Males: 3.59 ± 0.58 | Males: 13.0 | Males: 122.4 ± 21.5 | Males: 37.6 ± 13.4 | Males: 24.7 ± 6.1 | N/A | |
| Females: 52.1 ± 3.0 | Females: 3.5 ± 0.7 | Females: 12.9 | Females: 113.1 ± 22.6 | Females: 35.8 ± 14 | Females: 25.6 ± 5.4 | |||
| VI | Mixed18 (n = 229, male and female) | - | - | - | 130.5 (median) | - | - | N/A |
| VII | Mixed22 (n = 12; 7 males, 5 females) | - | Males: 3.4 ± 0.6 | - | Males: 151.8 ± 7.9 | Males: 50.1 ± 13.4 | Males: 23.5 ± 4.8 | No Data |
| Females: 2.9 ± 0.4 | Females: 114.3 ± 25.4 | Females: 36.2 ± 12.0 | Females: 23.7 ± 0.2 |
*
18 years or above,
n: number, n: reference