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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Mol Genet Metab. 2018 Mar 16;124(1):1–10. doi: 10.1016/j.ymgme.2018.03.004

Table 1.

Summary of growth in MPS

MPS Ethnic Population Mean Birth Length (cm) Mean Birth Weight (kg) Mean Birth BMI (kg/m2) Mean Final* Height (cm) Mean Final* Weight (kg) Mean Final* BMI (kg/m2) Relationship with Cognitive Impairment
I Polish3 (n = 16, all male) 55.3 ± 3.7 3.43 ± 0.7 11.2 - - - Yes
II Japanese10 (n= 111, all male) 50.31 ± 1.42 3.35 ± 0.39 13.2 ± 3.29 125.63 ± 9.09 37.18 ± 8.72 29.41 ± 6.15 No
Korean11 (n = 32, all male) - - - 127.7 (median, n = 7) - - No
Mixed7 (n = 676, all male) - - - - - - No
III Dutch13 (n = 118) 50.6 ± 1.7 3.5 ± 0.582 13.7 Males: 169.7 ± 9.3 Males: 60.1 ± 9.9 Males: 20.4 ± 2.2 Yes
Females: 165.4 ± 9.9 Females: 61.1 ± 11.6 Females: 20.2 ± 2.7
IVA Mixed6 (n = 388; 195 males, 193 females) Males: 52.4 ± 3.93 Males: 3.56 Males: 13.0 Males: 119.3 ± 22.6 Males: 36.5 ± 13.2 Males: 24.7 ± 6.1 N/A
Females: 52.1 ± 2.90 Females: 3.50 Females: 12.9 Females: 113.5 ± 23.1 Females: 35.2 ± 13 Females: 25.6 ± 5.4
Mixed14 (n = 354; 188 males, 166 females) Males: 52.5 ± 4.0 Males: 3.59 ± 0.58 Males: 13.0 Males: 122.4 ± 21.5 Males: 37.6 ± 13.4 Males: 24.7 ± 6.1 N/A
Females: 52.1 ± 3.0 Females: 3.5 ± 0.7 Females: 12.9 Females: 113.1 ± 22.6 Females: 35.8 ± 14 Females: 25.6 ± 5.4
VI Mixed18 (n = 229, male and female) - - - 130.5 (median) - - N/A
VII Mixed22 (n = 12; 7 males, 5 females) - Males: 3.4 ± 0.6 - Males: 151.8 ± 7.9 Males: 50.1 ± 13.4 Males: 23.5 ± 4.8 No Data
Females: 2.9 ± 0.4 Females: 114.3 ± 25.4 Females: 36.2 ± 12.0 Females: 23.7 ± 0.2
*

18 years or above,

n: number, n: reference