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. Author manuscript; available in PMC: 2018 Nov 2.
Published in final edited form as: Nature. 2018 May 2;557(7704):242–246. doi: 10.1038/s41586-018-0084-4

Figure 2. Telocytes express key signaling molecules.

Figure 2

RNAseq analysis of Foxl1+ cells (n=3 biologically independent animals) compared to Foxl1− mesenchymal cells (n=3 biologically independent animals), Lgr5+ stem cells (n=2 biologically independent animals), and differentiated enterocytes (n=2 biologically independent animals). (a) Heatmap showing hierarchical clustering. Only genes with a fold-change > 10 in pairwise comparisons and an FDR < 2% were used for the analysis. Values are normalized z-scores, plus or minus standard deviation. (b–g) Selected markers showing differential expression: (b) Foxl1, Pdgfra, Cd34 (telocyte markers), Lgr5 and Slc5a1, (c) Wnt pathway, (d) Bmp pathway, (e) Shh pathway, (f) Growth factors, (g) Tgfβ pathway. Data are shown as FPKM. Error bars indicate SEM.