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. 2018 May 23;8:8072. doi: 10.1038/s41598-018-26156-3

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Target genes analysis from microRNA clusters and families. (A) Graph bars depict the number of genes regulated by the number of microRNAs from clusters Chr 4.1 (miR-302), cluster miR-17-92 and cardiac microRNAs (miR-1, miR-133, miR-208, miR-490, miR-206, miR-499 and miR-143). (B) Gene Ontology (GO) terms from each group of microRNAs are shown in the dot plots. Dot size represents the number of genes included in each GO term and the colorimetric scale is based on the p-value. Gene Ratio represents the number of genes per the total number of genes in each GO term. (C) Correlation between the scores of the predicted targets were analyzed in pairwise for each member of the miR-302 cluster and represented in the scatter plots. Correlation scores are shown in the upper right portion of the graph and in the diagonal line are shown the density plots.