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Interactive effect of substantia nigra eQTL rs438811 for APOE with APOE ε4 status on AD risk.
| SNP | APOE ε4 carriers* | APOE ε4 non-carriers* | SNP × APOE ε4 status interaction* | |||
|---|---|---|---|---|---|---|
| OR (95% CI) | P-value | OR (95% CI) | P-value | OR (95% CI) | P-value | |
| rs438811 | 1.267 (1.124–1.430) | 1.12 × 10−4 | 0.882 (0.788–0.986) | 0.028 | 1.448 (1.231–1.704) | 7.94 × 10−6 |
*Adjusted for age and gender.
