Table 1.
Baseline population characteristics
| Variable | All n = 248 |
No previous MI n = 162 |
Previous MI n = 86 |
P value |
|---|---|---|---|---|
| Demographics—mean (SD) | ||||
| Age (years) | 64 (11.2) | 63.2 (11.3) | 65.4 (10.8) | .137 |
| Women/men (n) | 82/166 | 65/97 | 17/69 | .002 |
| BMI (kg/m2) | 27.8 (4.2) | 28.0 (4.3) | 27.4 (3.8) | .334 |
| Risk factors—n (%) | ||||
| Arterial hypertension | 149 (60) | 101 (62) | 48 (56) | .292 |
| Dyslipidemia | 141 (57) | 90 (56) | 51 (59) | .540 |
| Type 2 DM | 51 (21) | 25 (15) | 26 (30) | .007 |
| Smokers | 112 (45) | 65 (40) | 47 (55) | .021 |
| Cardiovascular history—n (%) | ||||
| Asymptomatic | 60 (24) | 54 (33) | 6 (7) | <.001 |
| Angina | 130 (52) | 80 (49) | 50 (58) | .178 |
| Dyspnea | 135 (54) | 75 (46) | 60 (70) | <.001 |
| Previous revascularization | 60 (24) | 15 (9) | 45 (52) | <.001 |
| Semiquantitative perfusion metrics—mean (SD) | ||||
| SRS | 4 (7) | 1 (1) | 10 (9) | <.001 |
| SSS | 9 (10) | 5 (6) | 17 (11) | <.001 |
| SDS | 5 (7) | 5 (6) | 7 () | .001 |
| Quantitative perfusion measurements—mean (SD) | ||||
| Rest MBF (mL/g/min) | 0.84 (0.34) | 0.87 (0.33) | 0.79 (0.34) | .073 |
| Stress MBF (mL/min/gr) | 1.99 (0.75) | 2.21 (0.73) | 1.55 (0.58) | <.001 |
| MPR | 2.55 (0.89) | 2.72 (0.89) | 2.18 (0.79) | <.001 |
| Ventricular function measurements—mean (SD) | ||||
| LVEF (systolic) | 61.6 (15.1) | 67.9 (9.7) | 49.0 (15.9) | <.001 |
| MFR/3 (diastolic) | 1.12 (0.38) | 1.21 (0.35) | 0.91 (0.36) | <.001 |
| Entropy (synchrony) | 45.6 (11.3) | 42.3 (8.7) | 52.8 (12.4) | <.001 |
BMI body mass index; DM diabetes mellitus; MI myocardial infarction; MBF myocardial blood flow; MPR myocardial perfusion reserve