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. 2018 May 17;12:317. doi: 10.3389/fnins.2018.00317

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Copyright © 2018 Zhang, Huang, Liu and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ROC curve of the dominant frequency as a performance measure to differentiate Parkinson's disease tremor and essential tremor, assuming targeting a diagnosis of essential tremor over Parkinson's disease. (A) Under the PSD estimate with Posture 1 (P1). AUC is 0.657 (95%CI 0.606–0.704) with a standard error of 0.025. (B) Under the bispectrum estimate with Posture 1 (P1). AUC is 0.671 (95%CI 0.621–0.716) with a standard error of 0.024. (C) Under the PSD estimate with Posture 2 (P2). AUC is 0.892 (95%CI 0.862–0.921) with a standard error of 0.015. (D) Under the bispectrum estimate with Posture 2 (P2). AUC is 0.870 (95%CI 0.835–0.902) with a standard error of 0.017.