Table 1.
GO analysis. Isolate-on genes are significantly over-represented in GO categories related to transcriptional regulation based on Fisher's test of adjusted p-values (α < 0.05). No categories were significantly over- or under-represented in the Tutored-on geneset.
| GO ID | GO description | expected | observed | adj. Fisher |
|---|---|---|---|---|
| Isolate-on | ||||
| 0003700 | sequence-specific DNA binding transcription factor activity | 46 | 82 | 0.00057 |
| 0005634 | nucleus | 201 | 265 | 0.00057 |
| 0043565 | sequence-specific DNA binding | 38 | 69 | 0.00096 |
| 0003677 | DNA binding | 81 | 123 | 0.001 |
| 0006355 | regulation of transcription, DNA-dependent | 60 | 95 | 0.0014 |
| 0004984 | olfactory receptor activity | 15 | 1 | 0.0014a |
| 0050911 | detection of chemical stimulus involved in sensory perception of smell | 15 | 1 | 0.0014a |
| 0007275 | multicellular organismal development | 13 | 29 | 0.0053 |
| 0005737 | cytoplasm | 165 | 210 | 0.026 |
| 0005515 | protein binding | 494 | 557 | 0.026 |
| 0000122 | negative regulation of transcription from RNA polymerase II promoter | 22 | 40 | 0.036 |
| 0045944 | positive regulation of transcription from RNA polymerase II promoter | 35 | 57 | 0.045 |
aCategories significantly under-represented.