Table 1. Capture methods and coverage summary of exome data.
Blood | AVM | |
---|---|---|
Capture method | Illumina Nextera Rapid Capture Exome Kit (transposase-based, bait set containing 38 Mb target territory) |
|
Mean coverage | 91.36 | 89.03 |
% Covered>10× | 96.2 | 95.5 |
% Covered>20× | 93.3 | 92 |
% Covered>30× | 88.5 | 86.6 |
% Zero coverage targets | 1.9 | 2 |
Abbreviation: AVM, arteriovenous malformation.
DNA obtained from formalin-fixed, paraffin-embedded tissue and whole blood.