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IL-1β, TNF-α, and transforming growth factor-β (TGF-β; A) together with intrarenal angiotensin II (B) levels were measured in whole kidney lysate using commercial enzyme immunoassays. Data are represented as individual values for each mouse (dots). Horizontal bars represent the means ± SE; *P < 0.05, **P < 0.01, and ****P < 0.0001 vs. the respective nondiabetic control.
