Fig. 2.
Lack of effect of endothelial denudation on the contraction to Na2S The trace shows an example of contractile responses to 30 μM and 1,000 μM Na2S, both applied in the presence of 5 μM PGF2α, in a pulmonary artery denuded of endothelium (note the absence of vasorelaxation to 10 μM carbachol). The bar chart (left) presents the means ± SE amplitudes of the 3 phases of the response to 1,000 μM Na2S in arteries in which the endothelium was left intact (black bars; n = 13) or denuded (gray bars; n = 20). The contractile responses to 30 μM Na2S in endothelium-intact (n = 30) and -denuded (n = 9) arteries are shown on the right. None of the responses were significantly different between endothelium-intact and -denuded arteries.