Fig. 7.

Effect of sulfide on ΔΨ in the absence and presence of myxothiazol. A, top trace: effect of applying 30 and then 500 μM Na₂S on ΔΨ. A, bottom trace: mitochondrial membrane potential during the application of the same concentrations of Na₂S following the prior application of 1 μM myxothiazol, which caused a slow depolarization of on ΔΨ. B: Bars represent the means ± SE of the peak monophasic hyperpolarization of ΔΨ by 30 μM Na₂S (left) and the 1st and 2nd hyperpolarizations of ΔΨ induced by 500 μM Na₂S in the presence of myxothiazol, each expressed as a percentage of that previously recorded in the same tissue under control conditions (n = 4) or in the presence of rotenone (n = 1). *P > 0.05, myxothiaziole vs control or rotenone by paired t-test (n = 5).