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. 2017 Dec 28;314(4):L670–L685. doi: 10.1152/ajplung.00283.2016

Fig. 10.

Fig. 10.

Effects of PKC, Rho kinase (ROCK), and NADPH oxidase (NOX) inhibitors on the contractile response to 1,000 μM sulfide. A: amplitudes of the peak of the phase 1 (Ph1) contraction (white bars), the nadir of the subsequent relaxation (gray bars), and peak of the phase 2 (Ph2) contraction evoked by 1,000 μM Na2S in PAs preconstricted with 5 μM PGF2α under control conditions (left) and in the presence of Gö6983 (3 μM) or VAS2870 (10 μM). B: effect of 10 min incubation in 500 μM Na2S on RhoA activation, normalized to paired control tissues. C: effect of 1 μM Y27632 on the contractile response to 500 μM Na2S. *P < 0.05, significantly different from the corresponding control value for that phase.