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. 2018 Jan 10;314(4):R611–R622. doi: 10.1152/ajpregu.00182.2017

Fig. 2.

Fig. 2.

A single injection of red blood cell (RBC)-specific antibody induced moderate anemia, with a nadir hemoglobin concentration of 89 ± 13 g/l observed on day 4 (n = 16; control n = 11; adjusted for 23 comparisons). A second injection of RBC-specific antibody induced severe anemia, reducing hemoglobin concentrations to 54 ± 5 g/l on day 5 (n = 6; control n = 6; adjusted for 23 comparisons). Hemoglobin values between control and anemic mice were not significantly different at 14 days following baseline injection. All data were analyzed by 2-way repeated-measures ANOVA. #P < 0.001 vs. control; $P < 0.001 vs. anemia/single injection.