Table 1.

Body weight, food intake, urine volume, and water intake in normoglycemic WT and NPY^−/− mice

	Body Weight, g	Food Intake, g/day	Urine Volume, ml/day	Water Intake, ml/day
WT mice (n = 5)
Control	26.3 ± 0.4	3.4 ± 0.2	2.2 ± 0.3	3.9 ± 0.3
MITII infusion	25.4 ± 0.7	2.8 ± 0.1	3.2 ± 0.6	4.6 ± 0.8
Recovery	27.1 ± 0.5	3.3 ± 0.4	3.7 ± 0.6	6.6 ± 1.0
NPY−/− (n = 7)
Control	27.3 ± 1.9	4.3 ± 0.2#	2.7 ± 0.5	4.3 ± 0.5
MTII infusion	27.1 ± 1.4	3.5 ± 0.3	1.4 ± 0.4	3.4 ± 0.3
Recovery	29.8 ± 1.3	3.6 ± 0.3	1.1 ± 0.4*	2.8 ± 0.3*

Values are means ± SE. WT, wild type; NPY, neuropeptide Y; MTII, melanotan II. Paired and unpaired Student’s t-test.

^*P < 0.05 compared with control period;

^#P < 0.05 compared with WT mice.