Fig. 2.
Interscapular brown adipose tissue surgery (iBATx) does not alter glycemic control and minimally affects lipid homeostasis. A: glucose tolerance test (GTT) conducted at 25 wk of age shows blood glucose levels following intraperitoneal injection of glucose (2 g/kg body wt). B: glucose area under the curve (AUC) during GTT. C: fasting hemoglobin A1c (HbA1c). D: homeostatic model assessment of insulin resistance (HOMA-IR). E and F: fasting plasma glucose and plasma insulin at 26 wk of age. G–J: fasting adipose tissue insulin resistance (AT-IR), nonesterified fatty acids (NEFA), liver triglycerides, and plasma cholesterol (total, HDL, and LDL) and triglycerides. Values are means ± SE; n = 10/group. DMain effect of diet (P < 0.05). iBATxMain effect of iBATx (P < 0.05).