. Author manuscript; available in PMC: 2018 Jun 1.

Published in final edited form as: Obstet Gynecol Clin North Am. 2018 Jun;45(2):249–265. doi: 10.1016/j.ogc.2018.01.010

Table 1.

The Curaçao criteria

Diagnostic criteria for HHT
Definite diagnosis: 3 criteria present
Possible or suspected diagnosis: 2 criteria present
Unlikely: <2 criteria present

Criteria

• Epistaxis	Spontaneous, recurrent nose bleeds

• Telangiectasias	Multiple, at characteristic sites Lips Oral cavity Fingers Nose

• Visceral lesions	Gastrointestinal telangiectasias
	Pulmonary AVM
	Hepatic AVM
	Cerebral AVM
	Spinal AVM

• Family history	First-degree relative with HHT

From Shovlin CL, Guttmacher AE, Buscarini E, et al. Diagnostic criteria for hereditary hemorrhagic telangiectasia (Rendu-Osler Weber syndrome). Am J Med Genet 2000;91(1):67; with permission.