Figure 2. G-CSF Treatment Significantly Improves Upon Pre-treatment RAWM Performance of Tg Mice.
Both Errors (upper) and Latency (lower) measures are presented. Comparing the last day of pre-testing to the last day of testing with concurrent G-CSF administration, mice in both NT groups showed continuing excellent performance irrespective of GCSF treatment. Tg control mice exhibited consistently poor performance for both pre- and during-treatment testing. By sharp contrast, Tg mice treated with GCSF showed significant improvements in both errors and latency during GCSF treatment. Pre-treatment mean ± SEM values are for all animals in that group. *p<0.05, **p<0.01 for pre-treatment versus during-treatment performance (paired t-test).