Table 4.
MINORS Criteria | Gutowski et al26 | Adams et al7 | Pfeiffer et al22 | Giordano et al25 | Drinane et al27 | Blount et al23 |
---|---|---|---|---|---|---|
1. A clearly stated aim | Unclear | Low risk | Low risk | Low risk | Low risk | High risk |
2. Inclusion of consecutive patients | Low risk | Unclear | Unclear | Low risk | Low risk | Low risk |
3. Prospective collection of data | High risk | Low risk | High risk | High risk | Low risk | High risk |
4. End points appropriate to the aim of the study | Unclear | Low risk | Low risk | Low risk | Low risk | Unclear |
5. Unbiased assessment of the study end point | Unclear | Unclear | High risk | Unclear | High risk | Unclear |
6. Follow-up period appropriate to the aim of the study | Low risk | Low risk | Low risk | Low risk | Low risk | Low risk |
7. Loss to follow-up less than 5% | Unclear | Unclear | Unclear | Unclear | Low risk | Unclear |
8. Prospective calculation of the study size | High risk | High risk | High risk | High risk | High risk | High risk |
9. An adequate control groupa | NA | NA | High risk | Low risk | Low risk | Unclear |
10. Contemporary groupsa (historical comparison) | NA | NA | High risk | High risk | Low risk | Low risk |
11. Baseline equivalence of groupsa | NA | NA | High risk | Unclear | Unclear | Unclear |
12. Adequate statistical analysesa | NA | NA | High risk | High risk | High risk | Low risk |
MINOR score | 6/16 (38%) | 9/16 (56%) | 13/24 (42%) | 14/24 (58%) | 20/24 (83%) | 11/24 (46%) |
Abbreviations. MINOR, Methodological index for non-randomized studies; NA, not applicable.