Table 4.

Standard Optimization Platform for Older Allogeneic Transplant Recipients Used at University of Chicago

Health Area	Standard Optimization Recommendations
GA	Interventions individualized based on GA-detected limitations in Table 2. Multidisciplinary team meeting and written optimization plan before transplant.
Comorbid conditions	Cultivate preferred subspecialists and request post-transplant follow-up. Referral to geriatrics or geriatric oncology for geriatric syndromes (eg, falls, incontinence).
Function	Structured prehabilitation based on baseline activity and limitations. Home safety assessment (fall risk, stairs, proximity of bathroom).
Social support	Pretransplant family meeting, caregiver present during cytopenia and “on-call” if issues. Request secondary caregivers. Enlist caregivers in optimization plan.
Cognition	Delirium awareness and precautions, medication avoidance, encourage presence of caregivers, add written material to verbal instructions, call patient to reinforce education.
Emotional health	Offer cognitive therapy and support group to avoid additional medications unless required
Nutrition	Develop nutritional plan before transplant included preferred supplements if used.
Medications	Reduce unnecessary medications. Re-evaluate days 30 to 100 post-transplant.
Other	Infection mitigation plan for grandchildren, evaluate remote drug allergies (eg, penicillin allergy in childhood), more frequent follow-up, smooth survivorship transition from transplant center.