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. 2018 May 24;9(6):627. doi: 10.1038/s41419-018-0646-2

Table 2.

Univariate and multivariate cox regression analyses of REGγ expression and overall cancer survival in patients with RCC

Univariate analysis Multivariate analysis
HR (95% CI) P Value HR (95% CI) P Value
REGγ expression
Low 1.0 (Reference) 1.0 (Reference)
High 2.126 (1.130–3.999) 0.019* 1.649 (1.327–3.287) 0.035*
Age
<60 1.0 (Reference) 1.0 (Reference)
≥60 1.549 (0.817–2.939) 0.180 1.232 (0.597–2.544) 0.572
Gender
Male 1.0 (Reference) 1.0 (Reference)
Female 1.271 (0.678–2.384) 0.455 1.461 (0.719–2.967) 0.294
Tumor side
Left 1.0 (Reference) 1.0 (Reference)
Right 0.93 (0.496–1.745) 0.822 0.917 (0.455–1.847) 0.807
Tumor size
≤4 cm 1.0 (Reference) 1.0 (Reference)
å 4 cm 2.007 (1.069–3.768) 0.030* 2.510 (1.089–5.781) 0.038*
T Stage
T1–T2 1.0 (Reference) 1.0 (Reference)
T3–T4 2.97 (1.489–5.921) 0.002* 3.393 (1.919–5.605) 0.045*
Fuhrman
I–II 1.0 (Reference) 1.0 (Reference)
III–IV 3.006 (1.475–6.374) 0.003* 1.597 (0.539–4.731) 0.198
Metastasis
Negative 1.0 (Reference) 1.0 (Reference)
Positive 2.349 (1.165–4.736) 0.017* 1.678 (0.898–4.033) 0.148

CI confidence interval, HR hazard ratio

* Statistically significant (p < 0.05)

p value from Cox regression analyses