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. 2018 May 24;9:2053. doi: 10.1038/s41467-018-04318-1

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — In vitro study of oxygen generating, PDT enhancement and cytotoxicity. a CLSM images of PDT-induced hypoxia reversion and intracellular ROS generation. The scale bars represent 20 μm. b Relative viabilities of L929 cells after incubation with various concentrations of UPC, UPP or UCPP without light irradiation for 48 h. c Relative cell viability of UPC-, UPP- or UCPP-treated HeLa cells under 980 nm light irradiation (5 min per every well) in hypoxic and normoxic environments. Data were shown as mean ± S.D. (n = 6)