Table 1.
Studies that have implemented TMS in the treatment of cocaine addicts
| n | TMS device and parameters | Target area | Control group | Assessment | Results | |
|---|---|---|---|---|---|---|
| Terraneo et al85 | 32 | rTMS (8-coil), 8 sessions, 40 trains, 15 Hz, 100% MT, 2,400 pulses | DlPfCx, left | Pharm | Urine, craving | More cocaine-free urine samples in rTMS group, reduction in craving in rTMS group |
| Rapinesi et al86 | 7 | rTMS (H coil), 12 sessions, 20 trains, 20 Hz, 100% MT, 720 pulses | DlPfCx, bilateral | No | Craving (VAS) | Reduction in craving |
| Bolloni et al87 | 10 | rTMS (H1 coil), 12 sessions, 20 trains, 10 Hz, 100% MT, 1,000 pulses | DlPfCx, bilateral | Sham TMS | Hair analysis | Reduction in Intake in 10 Hz rTMS group, no difference among subjects |
| Politi et al81 | 36 | rTMS (8-coil), 10 sessions, 20 trains, 15 Hz, 100% MT, 600 pulses | DlPfCx, left | No | Craving (VAS) | Reduction in craving |
| Camprodon et al79 | 6 | rTMS, 2 sessions, 20 trains, 10 Hz, 90% MT, 2,000 pulses | DlPfCx, right/left | No | Craving (VAS) | Reduction in craving with right rTMS |
| Hanlon et al92 | 11 | cTBS + fMRI, 1 session, 110% MT, 1,800 pulses | MPfCx, left | Sham TMS | Craving | Reduction in craving |
Abbreviations: rTMS, repetitive transcranial magnetic stimulation; MT, motor threshold; cTBS, continuous θ-burst stimulation; fMRI, functional magnetic resonance imaging; DlPfCx, dorsolateral prefrontal cortex; MPfCx, medial prefrontal cortex; VAS, visual analogue scale.