TABLE 2. (B).

Results of the Hypergeometric P-Value Calculation Used to Generate Hypothesis on Possible Categorical Predictors of the Subnetworks Membership

ID	Variable	Value	Fraction in subnet1-fraction in subnet2	Hypergeometric P-value
6	demographic_race.asian	1	8.68%	2.44E-04
6	demographic_race.asian	0	−8.18%	5.81E-04
60	morphMRI_WORMS_cartilage.MF	0	6.79%	0.001337
28	PROMs_IPAQ.categorical	1	6.96%	0.002840
36	morphMRI_WORMS_meniscusLes.bodyMED	0	6.03%	0.003500
7	demographic_race.white/caucasian	0	7.15%	0.003585
61	morphMRI_WORMS_cartilage.LF	0	5.24%	0.004725
7	demographic_race.white/caucasian	1	−6.64%	0.006429
37	morphMRI_WORMS_meniscusLes.PHMED	0	6.54%	0.007321
23	PROMs_Womac.stifness	100	6.37%	0.008294
47	morphMRI_WORMS_meniscusTot.MED	0	5.72%	0.017170
21	PROMs_Koos.QOL	100	4.92%	0.021869
10	Xray_KL	3	−3.57%	0.024024
16	PROMs_Marx.sum	9	2.19%	0.026122
20	PROMs_Koos.sport	85	−2.52%	0.027823
37	morphMRI_WORMS_meniscusLes.PHMED	3	−2.52%	0.027823
28	PROMs_IPAQ.categorical	2	−5.11%	0.030478
69	morphMRI_WORMS_BMEL.LT	0	3.32%	0.032345
18	PROMs_Koos.symtoms	89.29	−2.92%	0.033614
40	morphMRI_WORMS_meniscusLes.PHLAT	0	4.79%	0.034102
62	morphMRI_WORMS_cartilage.MT	0	3.47%	0.037707
18	PROMs_Koos.symtoms	100	3.99%	0.039162
10	Xray_KL	0	4.69%	0.040054
21	PROMs_Koos.QOL	93.75	−2.27%	0.040304
47	morphMRI_WORMS_meniscusTot.MED	4	−2.27%	0.040304
23	PROMs_Womac.stifness	75	−3.76%	0.042801
57	morphMRI_WORMS_cartilagetype.tfjOA	3	−3.76%	0.042801
49	morphMRI_WORMS_ligament.ACL	0	3.91%	0.043402
5	demographic_gender	2:male	4.65%	0.044364
68	morphMRI_WORMS_BMEL.MT	0	2.67%	0.046153

Overall variables dictionary is included as Supplementary Material.