Table 4.
Patient reported function and quality of life (QoL) based on Subjective Significance Questionnaire
| Assessment Time Points | Mid-Treatment | 1 Month Post-chemotherapy | 12 month Post-Chemotherapy | 18 Months Post chemotherapy | 24 Month Post-chemotherapy | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Chemotherapy preference | High | Low | P | High | Low | P | High | Low | P | High | Low | P | High | Low | P |
| Has your overall physical condition gotten: | |||||||||||||||
| Any worse | 8 (13.6) |
23 (34.3) |
0.005 | 8 (15.1) |
13 (18.6) |
0.74 | 4 (7.0) |
3 (5.2) |
0.65 | 7 (13.7) |
8 (14.0) |
0.87 | 6 (11.8) |
10 (18.2) |
0.59 |
| About the same | 29 (49.2) |
33 (49.2) |
25 (47.2) |
35 (50.0) |
23 (40.4) |
19 (32.8) |
20 (39.2) |
25 (43.9) |
27 (52.9) |
29 (52.7) |
|||||
| Any better | 22 (37.3) |
11 (16.4) |
20 (37.7) |
22 (31.4) |
30 (52.6) |
36 (62.1) |
24 (47.1) |
24 (42.1) |
18 (35.3) |
16 (29.1) |
|||||
| Has your overall emotional state gotten: | |||||||||||||||
| Any worse | 3 (5.1) |
12 (17.9) |
0.012 | 3 (5.6) |
8 (11.4) |
0.40 | 2 (3.5) |
3 (5.2) |
0.99 | 3 (5.9) |
5 (8.8) |
0.87 | 0 | 5 (9.1) |
0.10 |
| About the same | 33 (55.9) |
42 (62.7) |
33 (61.1) |
44 (62.9) |
23 (40.4) |
24 (41.4) |
26 (51.0) |
29 (50.9) |
35 (68.6) |
33 (60.0) |
|||||
| Any better | 23 (39.0) |
13 (19.4) |
18 (33.3) |
18 (25.7) |
32 (56.1) |
31 (53.4) |
22 (43.1) |
23 (40.4) |
16 (31.4) |
17 (30.9) |
|||||
| Has ability to enjoy your social life gotten: | |||||||||||||||
| Any worse | 4 (6.9) |
17 (25.4) |
0.003 | 6 (11.1) |
10 (14.3) |
0.15 | 1 (1.8) |
2 (3.4) |
0.73 | 4 (7.8) |
4 (7.0) |
0.64 | 2 (3.9) |
5 (9.1) |
0.65 |
| About the same | 31 (53.4) |
38 (56.7) |
27 (50.0) |
44 (62.9) |
27 (47.4) |
24 (41.4) |
24 (47.1) |
32 (56.1) |
34 (66.7) |
35 (63.6) |
|||||
| Any better | 23 (39.7) |
12 (17.9) |
21 (38.9) |
16 (22.9) |
29 (50.9) |
32 (55.2) |
23 (45.1) |
21 (36.8) |
15 (29.4) |
15 (27.3) |
|||||
| Has your overall quality of life gotten: | |||||||||||||||
| Any worse | 5 (8.5) |
18 (27.3) |
0.004 | 8 (14.8) |
11 (15.9) |
0.14 | 1 (1.8) |
4 (6.9) |
0.19 | 4 (7.8) |
5 (8.8) |
0.96 | 3 (5.9) |
6 (10.9) |
0.63 |
| About the same | 31 (52.5) |
36 (54.6) |
23 (42.6) |
40 (58.0) |
24 (42.1) |
17 (29.3) |
23 (45.1) |
27 (47.4) |
31 (60.8) |
34 (61.8) |
|||||
| Any better | 23 (40.0) |
12 (18.2) |
23 (42.6) |
18 (26.1) |
32 (56.1) |
37 (63.8) |
24 (47.1) |
25 (43.9) |
17 (33.3) |
15 (27.3) |
|||||