Table 2.
Acid-base measurements from serum and urine in the overall cohort and by urine ammonium excretion rate tertiles
| Acid-Base Measurement | Total Cohort, n=144 | NH4+ Tertile 1 (0.3–0.8 mEq/h), n=48 | NH4+ Tertile 2 (0.9–1.3 mEq/h), n=48 | NH4+ Tertile 3 (1.4–5.3 mEq/h), n=48 |
|---|---|---|---|---|
| Urine | ||||
| NH4+, mEq/h | 1.27 (0.72) | 0.66 (0.14) | 1.11 (0.16) | 2.03 (0.74) |
| Titratable acid, mEq/h | 1.14 (0.65) | 0.66 (0.37) | 1.03 (0.42) | 1.72 (0.61) |
| NH4+ + titratable acid, mEq/h | 2.41 (1.27) | 1.32 (0.46) | 2.15 (0.47) | 3.75 (1.18) |
| NH4+, mEq/kg per day | 0.31 (0.16) | 0.18 (0.06) | 0.29 (0.07) | 0.47 (0.16) |
| Titratable acid, mEq/kg per day | 0.28 (0.15) | 0.17 (0.09) | 0.26 (0.10) | 0.40 (0.15) |
| NH4+ + titratable acid, mEq/kg per day | 0.59 (0.28) | 0.35 (0.13) | 0.55 (0.14) | 0.87 (0.27) |
| pH | 5.6 (0.5) | 5.8 (0.6) | 5.6 (0.5) | 5.4 (0.3) |
| pH≥6.5, no. (%) | 7 (5) | 5 (10) | 2 (4) | 0 (0) |
| Serum | ||||
| Bicarbonate, mEq/L | 23 (3) | 23 (2) | 23 (3) | 23 (3) |
| Bicarbonate <22 mEq/L, no. (%) | 36 (25) | 9 (19) | 15 (31) | 12 (25) |
| Bicarbonate 22–28 mEq/L, no. (%) | 106 (74) | 39 (81) | 32 (67) | 35 (73) |
| Bicarbonate >28 mEq/L, no. (%) | 2 (1) | 0 (0) | 1 (2) | 1 (2) |
Continuous variables are presented as mean (SD), and categorical variables are presented as number (percentage). NH4+, ammonium.