TABLE1.
Fold change in antioxidant genes at 72 h
Genes | Sal 50% |
Sal IH |
Cat Nx |
Cat 50% |
Cat IH |
MnT Nx |
MnT 50% |
MnT IH |
EUK Nx |
EUK 50% |
EUK IH |
---|---|---|---|---|---|---|---|---|---|---|---|
CAT | −5.5 | 1.9 | −19.2 | −2.7 | −18.4 | −48.6 | −7.1 | −2.9 | −15.0 | −28.4 | −5.9 |
GPX1 | −2.1 | −1.1 | −1.7 | 1.3 | −1.9 | −2.4 | −2.4 | −2.4 | −1.2 | −2.4 | −2.4 |
GPX2 | −26.7 | 1.2 | −14.9 | −17.7 | −4.6 | −128.8 | −113.0 | −5.7 | −76.4 | −165.2 | −46.0 |
GPX3 | −2.2 | 1.7 | −5.1 | −4.5 | −6.6 | −21.8 | −6.9 | −2.1 | −3.3 | 1.0 | −21.8 |
GPX4 | −1.4 | 1.5 | −2.5 | −4.4 | −4.9 | −38.4 | −6.2 | −1.6 | −3.8 | −1.8 | −20.2 |
GPX5 | −4.7 | 2.0 | −5.1 | −5.6 | −2.4 | −111.4 | −28.6 | −1.6 | −22.0 | −38.2 | −9.3 |
GPX6 | −1.3 | 1.3 | −2.4 | −2.4 | 1.6 | −2.4 | −1.9 | −2.0 | −1.0 | 1.4 | −2.4 |
SOD1 | −2.8 | 1.1 | −8.0 | −2.6 | −1.9 | −144.8 | −2.8 | −2.5 | −4.1 | −4.2 | −2.7 |
SOD2 | −3.3 | −1.1 | −11.7 | −2.1 | 1.2 | −152.6 | −3.1 | −2.0 | −4.4 | −3.2 | −2.4 |
SOD3 | −1.5 | 1.0 | 1.0 | 1.2 | −1.1 | −1.4 | 1.1 | −1.4 | 1.1 | −1.5 | 1.3 |
Note: Genes of interest are: CAT (catalase); GPX (glutathione peroxidase); SOD (superoxide dismutase). Data are fold change from saline treatment in normoxic conditions (Sal Nx). Genes that are >5-fold downregulated are in red font. Sal (saline); Cat (catalase); MnT (MnTBAP); EUK (EUK-134); Nx (normoxia); IH (intermittent hypoxia).