Table 4.
Associations of dialysis standard Kt/V with clinical outcomes in patients treated with home hemodialysis and in-center hemodialysis
| stdKt/V | Hazard Ratio (95% Confidence Interval) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Mortality | Hospitalization | Transfer to In-Center HD | |||||||
| Unadjusted | Minimally Adjusteda | Fully Adjustedb | Unadjusted | Minimally Adjusteda | Fully Adjustedb | Unadjusted | Minimally Adjusteda | Fully Adjustedb | |
| Home HD | |||||||||
| <2.1 | 0.93 (0.66 to 1.33) | 0.95 (0.66 to 1.37) | 1.03 (0.71 to 1.48) | 1.05 (0.91 to 1.23) | 1.07 (0.92 to 1.25) | 1.08 (0.93 to 1.26) | 1.23 (0.94 to 1.61) | 1.23 (0.94 to 1.62) | 1.24 (0.94 to 1.64) |
| mid | Reference | Reference | Reference | Reference | Reference | Reference | Reference | Reference | Reference |
| ≥2.3 | 1.04 (0.71 to 1.52) | 1.22 (0.82 to 1.83) | 1.08 (0.73 to 1.60) | 1.04 (0.88 to 1.23) | 1.05 (0.88 to 1.24) | 1.03 (0.87 to 1.22) | 1.10 (0.81 to 1.49) | 1.11 (0.82 to 1.50) | 1.15 (0.85 to 1.56) |
| In-center HD | |||||||||
| <2.1 | 0.99 (0.96 to 1.02) | 1.08 (1.05 to 1.12) | 1.11 (1.07 to 1.14) | 1.06 (1.04 to 1.08) | 1.09 (1.07 to 1.11) | 1.10 (1.08 to 1.12) | — | — | — |
| mid | Reference | Reference | Reference | Reference | Reference | Reference | — | — | — |
| ≥2.3 | 1.06 (1.03 to 1.09) | 1.02 (0.99 to 1.05) | 0.97 (0.94 to 0.99) | 1.08 (1.06 to 1.09) | 1.03 (1.02 to 1.05) | 1.01 (0.99 to 1.02) | — | — | — |
stdKt/V, standard Kt/V; HD, hemodialysis; —, not applicable.
a
Data adjusted for age, sex, and race/ethnicity.
b
Data adjusted for demographic characteristics (age, sex, and race/ethnicity) plus body mass index, diabetes status, history of congestive heart failure, history of atherosclerotic heart disease, serum albumin, and vascular access type.