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Patient autoantibodies recognize conformation-dependent epitopes in thrombospondin type 1 domain–containing 7A (THSD7A). Images depict Western blots of full-length THSD7A, the three THSD7A fragments, and the small thrombospondin type 1 (TSP-1) domain constructs with one representative serum (MN 27) under nonreducing (upper panels) and reducing conditions (lower panels).
