Table 2.
Overview of studies evaluating changes in LV diastolic function echocardiographic indices during hemodialysis and association with intradialytic volume changes
| Author | Year | N | Time of Evaluation | Main Finding | Diastolic Function Change | Association between Changes in Indices and Volume | Volume Marker |
|---|---|---|---|---|---|---|---|
| Drighil et al.30 | 2008 | 17 | Before and after hemodialysis | LV E and E/A ratio, and RV E decrease | Deterioration | Yes (+) | Intradialytic weight loss |
| Sadler et al.31 | 1992 | 24 | Before, at 2 h, and after hemodialysis | LV and RV E and E/A ratio decrease | Deterioration | Yes (+) | Intradialytic weight loss |
| Dubin et al.32 | 2014 | 35 | Before and during the last hour of hemodialysis | LV E/Em ratio decrease | Deterioration | Yes (+) | NT-proBNP |
| Fijalkowski et al.33 | 2006 | 25 | Before and after hemodialysis | LV E and E/Em decrease | Deterioration | Yes (+) | Intradialytic weight loss |
| Graham et al.35 | 2003 | 17 | Before and after hemodialysis | LV E and E/A ratio decrease | Deterioration | No | Intradialytic weight loss |
| Assa et al.36 | 2013 | 109 | Before, at 60 and 180 intradialytic minutes, and after hemodialysis | LV E and Em decrease | Deterioration | No | BNP |
| Sarafidis et al.29 | 2016 | 41 | Before and after two separate hemodialysis sessions | LV and RV E decrease | Deterioration | Yes (+) | Intradialytic weight loss |
Studies are presented in chronologic order (“+” is used to present a positive correlation). E and Em, early non–tissue-Doppler and tissue-Doppler diastolic velocities (accordingly); A, late diastolic velocity; NT-proBNP, N-terminal pro b-type natriuretic peptide; BNP, brain natriuretic peptide.