Figure 2.

Nine of the 17 biomarkers measured on the first day of AKI were higher in children with AKI progression. Urine and plasma biomarkers were measured on the first day of serum creatinine–defined AKI. The y axis is displayed on a logarithmic scale. Boxes represent the median and interquartile range (25th and 75th percentiles), and whiskers represent the range of values. The asterisks represent a significant difference (P<0.05) in comparison of AKI and non-AKI progression. Cr, creatinine; KIM-1, kidney injury molecule 1; L-FABP, liver fatty acid binding protein; NGAL, neutrophil gelatinase–associated lipocalin.