Table 1.
Drosophila strains used
| Genotype | Description | Source | Ref. |
|---|---|---|---|
| w; c42-GAL4 | Principal cell GAL4 driver | Laboratory of Dow/Davies | Rosay et al.62 |
| w; tub-GAL80ts20 | Temperature-sensitive GAL4 repressor | BDSC 7019 | McGuire et al.66 |
| w; UAS-DmWNKRNAi | RNAi against Drosophila WNK | BDSC 42521 | |
| w; UAS-DmMo25RNAi | RNAi against Drosophila Mo25 | VDRC 34788 | Dietzl et al.67 |
| w; UAS-ClopHensor c304 | pH/chloride sensor | This study | |
| w; UAS-SPAKD219A | WNK substrate | This study | |
| w; UAS-DmWNKWT | Drosophila WNK | This study | |
| w; UAS-DmWNKL421F | Chloride-insensitive Drosophila WNK | This study | |
| w; UAS-DmMo25 | Drosophila Mo25 | This study | |
| w; UAS-MmMo25 | Mouse Mo25 | This study | |
| w;UAS-FrayT206E | Fray phosphomimicking mutation | Laboratory of A.R.R. | Wu et al.18 |
BDSC, Bloomington Drosophila Stock Center (Indiana University, Bloomington, IN); DmWNK, D. melanogaster With No Lysine kinase; RNAi, RNA interference; WNK, With No Lysine kinase; DmMo25, D. melanogaster mouse protein 25; Mo25, mouse protein 25; VDRC, Vienna Drosophila Resource Center (Vienna, Austria); WT, wild type.